2018/01 – 2019/01，美国华盛顿大学，医学院，访问学者，
2011/08 - 2011/11，香港浸会大学，化学系，高级访问学者
2009/11 - 2010/11，英国剑桥大学，生物化学系，访问学者
2004/01 - 2011/08，厦门大学，物理学系，副教授
2001/10 - 2004/01，西安电子科技大学，电子工程研究所，博士后
学历：
福建师范大学 理学学士，物理学专业
福建师范大学 理学硕士，光学专业
厦门大学 理学博士，凝聚态物理
研究方向：
机器学习、空间组学、计算质谱、质谱成像、分子网络建模、健康大数据
主讲课程：
数字图像处理（本科生课）
数字信号与图像处理实验（本科生课）
Matlab程序设计（本科生课）
高维数据分析与建模（研究生课）
机器学习（研究生课）
课题项目：
多尺度代谢互作网络分析新方法应用于阿尔兹海默病空间代谢组学研究, 国家自然科学基金（面上）项目，2024.01 - 2027.12,主持
基于信息熵的网络分析新方法及其在肝细胞肝癌代谢组学研究中的应用，国家自然科学基金（面上）项目，2019.01-2022.12，主持
基于NAMPT/SIRT1 对脂代谢的调控作用研究清络饮从湿论治热痹的原理，国家自然科学基金（面上）项目，2020.01-2023.12，共同主持
代谢组学数据融合与建模新方法及在糖尿病肾病研究中的应用，国家自然科学基金（面上）项目，2014.01-2017.12，主持
基于多尺度空间代谢组学的阿尔兹海默病早期诊断及分子机制研究，福建省社会发展引导性项目，2022.03 - 2025.02，主持
核磁共振代谢轮廓分析新技术及在妊娠期糖尿病研究中的应用，福建省社会发展引导性项目，2015.04-2018.03，主持
核磁共振代谢组学新方法的研究及在糖尿病肾病早期诊断中的应用，福建省自然科学基金（面上）项目,2009.03-2011.09，主持
物理智能磁共振成像及应用，福建省自然科学基金(重点)项目. 2023.08 -2026.08，参与
基于代谢表型的网络分析新方法及其在腧穴配伍效应评价中的应用. 福建省自然科学基金(面上)项目. 2020.11 - 2023.10, 参与
代表作(2021年以来)：
Yikun Zhou, Shuang Gao, Lingli Deng*, Genjin Lin, Jiyang Dong*. A Group based Network Analysis for Alzheimer’s Disease fMRI Data. Scientific Reports. 2025 (2区)
Yongpei Wang, Zeyu Zhu, Lingli Deng, Kian-Kai Cheng, Fanjing Guo, Genjin Lin, Daniel Raftery*, Jiyang Dong*, Multiscale Synergy Networks Offer Insights into Diseases and Comorbidity Mechanisms. Analytical Chemistry. 2025, 97 (6): 3633–3642 (1区top)
Caixia Yuan#, Dandan Zhang#, Hairong Zhang, Jiyang Dong*, Caisheng Wu*. Breaking barriers: MS-BDF tools in the quality control of insect-derived traditional Chinese medicine. Journal of Pharmaceutical Analysis, 2025 (1区)
Lei Guo, Peisi Xie, Xionghui Shen, Ka Yam Lam, Lingli Deng, Chengyi Xie, Xiangnan Xu, Chris Kong Chu Wong, Jingjing Xu, Jiacheng Fang, Xiaoxiao Wang, Zhuang Xiong, Shangyi Luo, Jianing Wang, Jiyang Dong*, Zongwei Cai*. Unraveling Spatial Heterogeneity in Mass Spectrometry Imaging Data with GraphMSI. Advance Science. 2025, 12, 2410840 (1区top)
Zhouao Zhou, Xinli Liao, Xu Qiu, Yue Zhang, Jiyang Dong, Xiaobo Qu, Donghai Lin*. NMRformer: A Transformer-based Deep Learning Framework for Peak Assignment in 1D 1H NMR Spectroscopy. Analytical Chemistry. 2025, 97 (1): 904–911 (1区top)
Yufei Huang, Feifei Lu, Yang Guo, Kian-Kai Cheng, Zijian Wang, Wei Li, Jiyang Dong, Biao Huang*, Xiaohong Cui*. Solvent Selection in the Quality Analysis of White Tea by Nuclear Magnetic Resonance Spectroscopy. LWT-- Food Science and Technology. 2025, 215, 117155. (1区top)
Caixia Yuan#, Ying Jin#, Hairong Zhang, Simian Chen, Jiajin Yi, Qiang Xie*, Jiyang Dong*, Caisheng Wu*. An efficient and affordable strategy to empower nontargeted metabolomics combining three-dimensional combinatorial derivatization with MS-TDF software. Analytical Chemistry, 2024, 96 (19): 7634-7642(1区top)
Mudassir Shah, Lei Guo, Xiangnan Xu, Lingli Deng, Keyi Lu, Jiyang Dong, Chao Zhao*, Jingjing Xu*. eLIMS: Ensemble Learning-Based Spatial Segmentation of Mass Spectrometry Imaging to Explore Metabolic Heterogeneity. Journal of Proteome Research. 2024, 23. (2区)
Yirong Zhou, Chen Qian, Jiayu Li, Zi Wang, Yu Hu, Biao Qu, Liuhong Zhu, Jianjun Zhou, Taishan Kang, Jianzhong Lin, Qing Hong, Jiyang Dong, Di Guo, Xiaobo Qu. CloudBrain-ReconAI: A Cloud Computing Platform for MRI Reconstruction and Radiologists' Image Quality Evaluation. IEEE Transactions on Cloud Computing. 2024, 12(4): 1359-1371 (2区)
Shiting Qian, Qinqin Yang, Congbo Cai, Jiyang Dong, Shuhui Cai*. A study of spatial-temporal characteristics of autism fMRI by combining hidden Markov model and dynamic graph theory. Brain Science. 2024 (3区)
Yinghe Zhao, Qinqin Yang, Shiting Qian, Jiyang Dong, Shuhui Cai, Zhong Chen, Congbo Cai*. Improving the sensitivity of task-based multi-echo functional magnetic resonance imaging via T2* mapping using synthetic data-driven deep learning. Brain Science. 2024, 14: 828. (3区)
Lei Guo#, Chengyi Xie#, Rui Miao, Jingjing Xu, Xiangnan Xu, Jiacheng Fang, Xiaoxiao Wang, Wuping Liu, Xiangwen Liao*, Jianing Wang*, Jiyang Dong*, Zongwei Cai*. DeepION: a deep learning-based low-dimensional representation model of ion images for mass spectrometry imaging. Analytical Chemistry, 2024, 96 (9): 3829–3836. (1区top)
Xiaodie Chen, Jiayu Li, Dicheng Chen, Zhangren Tu, Meijin Lin, Taishan Kang, Jianzhong Lin, Tao Gong, Liuhong Zhu, Jianjun Zhou, Lin Ou-yang, Jiefeng Guo, Jiyang Dong, Di Guo, Xiaobo Qu*. CloudBrain-MRS: An Intelligent Cloud Computing Platform for in vivo Magnetic Resonance Spectroscopy Preprocessing, Quantification, and Analysis. Journal of Magnetic Resonance. 2024, 358, 107601 (3区)
Xingxing Liu, Yifan Wu, Lei Guo, Xiaoyu Wang, Changkai Shan, Yaru Liu, Hanxiang An, Xinmei Kang, Rong Ding, Zongwei Cai, Jiyang Dong*, Yufen Zhao*, Xiang Gao*. Comprehensive Profiling of Amine-Containing Metabolite Isomers with Chiral Phosphorus Reagents. Analytical Chemistry, 2023, 95 (46):16830–16839 (1区top)
Biao Qu, Xiaoyuan Li, Min Xiao, Runhan Chen, Hejuan Tan, Hongwei Sun, Rushuai Li, Jingjing Xu, Jiyang Dong, Gaofeng Zheng, Shuyue Ai*, Xiaobo Qu*. Comparative study of bilateral putamen for patients with severe Parkinson’s disease detected by 1H magnetic resonance spectroscopy. Quantitative Imaging in Medicine and Surgery. 2023. doi: 10.21037/qims-23-231 (3区)
Xue Bai#, Caixia Yuan#, Jiyang Dong, Xiaojun Jiang, Xiaoyu Qian, Shaogui He, Xiaodan Guo, Tie Cai*, Dunming Xu*, Caisheng Wu*. Rapid and accurate identification of adulterated ingredients in lotus root powder based on liquid chromatography-high resolution mass spectrometry and MS-IDF. Journal of Food Composition and Analysis, 2023, 123:105576. (2区)
Genjin Lin, Liheng Dong, Kian-Kai Cheng, Xiangnan Xu, Yongpei Wang, Lingli Deng*, Daniel Raftery, Jiyang Dong*. Differential Correlations Informed Metabolite Set Enrichment Analysis to Decipher Metabolic Heterogeneity of Disease. Analytical Chemistry, 2023, 95 (33): 12505-12513 (1区top)
Lei Guo, Jinyu Zhu, Keqi Wang, Kian-Kai Cheng, Jingjing Xu, Liheng Dong, Xiangnan Xu, Can Chen, Mudassir Shah, Zhangxiao Peng, Jianing Wang, Zongwei Cai, Jiyang Dong*. Multimodal Image Fusion Offer Better Spatial Resolution for Mass Spectrometry Imaging. Analytical Chemistry, 2023, 95(25): 9714–9721 (1区top)
Congcong Guo#, Jiyang Dong#, lingli Deng, Kian-Kai Cheng, Yue Xu, Haowen Zhu, Anjun Deng, Qinhai Lin*, Yinghong Wang*. Application of bs-HSQC-NMR in Species identification and Adulteration behavior analysis of Panax Linn. Molecules, 2023, 28, 4332 (2区top)
Fanjing Guo, Genjin Lin, Liheng Dong, Kian-Kai Cheng, Lingli Deng, Xiangnan Xu, Daniel Raftery*, Jiyang Dong*. Conccordance-Based Batch Effect Correction Method for Large-Scale Metabolomics. Analytical Chemistry. 2023, 95(18): 7220-7228 (1区top)
Xiaoyu Wang#, Chunjing Chen#, Yaohui He#, Lianshuai Ding, Yifan Wu, Chengting Huang, Jun Wu, Rong Ding, Yuhua Xue, Zhiwei Lin, Pengxiang Xu, Yile Wu, Wen Liu, Jijun Li, Zongwei Cai, Yufen Zhao, Jiyang Dong*, Qiang Zhou*, Xiang Gao*. Isobaric stable isotope N-Phosphorylation labeling (iSIPL) for accurate and sensitive proteome quantification. Angewandte Chemie International Edition. 2023, 62: e202303656. (1区top)
Yongpei Wang#, Xingxing Liu#, Liheng Dong, Kian-Kai Cheng, Caigui Lin, Xiaomin Wang, Jiyang Dong*, Lingli Deng*, Daniel Raftery. iMSEA: A Novel Metabolite Set Enrichment Analysis Strategy to Decipher Drug Interactions. Analytical Chemistry. 2023, 95(15): 6203-6211 (1区top)
G. A. Nagana Gowda*, Vadim Pascua, John A. Lusk, Natali N. Hong, Lin Guo, Jiyang Dong, Ian R. Sweet, Daniel Raftery*. Monitoring Live Mitochondrial Metabolism in Real-Time Using NMR Spectroscopy. Magnetic Resonance in Chemistry. 2023,61:718-727(3区)
Jiyang Dong, Qianwen Peng, Lingli Deng, Chao Zhao*, Zongwei Cai*. Protocol for metabolic synergy analysis of multi-organs in mice using iMS2Net. STAR Protocols, 2023, 4: 102159. (4区)
Lei Guo#, Jiyang Dong#,*, Xiangnan Xu, Zhichao Wu, Yinbin Zhang, Yongwei Wang, Pengfei Li, Chao Zhao*, Zongwei Cai*. Divide-and-conquer: a flexible deep learning strategy for exploring metabolic heterogeneity from mass spectrometry imaging data. Analytical Chemistry, 2023, 95 (3): 1924-1932 (1区top)
Caigui Lin#, Qing Hu#, Jiyang Dong, Zhiliang Wei, Jie Li*, Zhong Chen*. Serum metabolic signatures of schizophrenia patients complicated with hepatitis B virus infection: A 1H NMR-based metabolomics study. Frontiers in Psychiatry, 2022, 13: 998709 (3区)
Xin Liu, Yue Li, Chunjing Chen, Jiyang Dong, Jie Zhou, Lei Wang, Xiang Gao, Xinmei Kang*. Exosomal EphA2 Promotes Tumor Metastasis of Triple-Negative Breast Cancer by Destroying Endothelial Barrier. Clinical & Experimental Metastasis, 2022, 40(1): 105-116 (3区)
Lei Guo#, Xingxing Liu#, Chao Zhao, Zhenxing Hu, Xiangnan Xu, Kian-Kai Cheng, Mudassir Shah, Jingjing Xu*, Jiyang Dong *, Zongwei Cai. iSegMSI: An Interactive Strategy to Improve Spatial Segmentation of Mass Spectrometry Imaging Data. Analytical Chemistry. 2022, 94 (42): 14522-14529. (1区top)
Jiyang Dong, Qianwen Peng, Lingli Deng, Jianjun Liu, Wei Huang, Xin Zhou, Chao Zhao*, Zongwei Cai*. iMS2Net: A Multiscale Networking Methodology to Decipher Metabolic Synergy of Organism. iScience. 2022, 25(9): 104896 (2区)
Chao Zhao, Jiyang Dong, Lingli Deng, Yawen Tan, Wei Jiang, Zongwei Cai*. Molecular Network Strategy in Metabolomics and Mass Spectrometry Imaging. Current Opinion in Chemical Biology, 2022, 70:102199 (2区)
Qinqin Yang, Jiechao Wang, Jianfeng Bao, Xiaoyin Wang, Lingceng Ma, Qizhi Yang, Shuhui Cai, Hongjian He, Congbo Cai*, Jiyang Dong*, Zhong Chen, Jianhui Zhong. MOdel-based SyntheTic Data-driven Learning (MOST-DL): Application in Single-shot T2 Mapping with Severe Head Motion Using Overlapping-echo Acquisition. IEEE Transactions on Medical Imaging. 2022, 41 (11): 3167-3181. (1区top)
Suping Wang#, Xiaojuan Jiang#, Rong Ding, Binbin Chen, Haiyan Lyu, Junyang Liu, Chunyan Zhu, Rong Shen, Jiayun Chen, Yun Hong, Yun-long Wu, Jiyang Dong*, Caisheng Wu*. MS-IDF: A Software Tool for Nontargeted Identification of Endogenous Metabolites after Chemical Isotope Labeling Based on a Narrow Mass Defect Filter. Analytical Chemistry. 2022, 94 (7): 3194-3202 (1区top)
Dandan Wang#, Xinyue Wu#, Jiyang Dong, Xiuping Cheng, Shaofei Gu,Opeyemi Joshua Olatunji, Yan Li*, Jian Zuo*. Qing-Luo-Yin alleviated experimental arthritis in rats by disrupting immune feedback between inflammatory T cells and monocytes: Key evidences from its effects on immune cell phenotypes. Journal of Inflammation Research, 2021, 14: 7467-7486. (2区)
Jingjing Xu, Yuanshan Wang, Xiangnan Xu, Kian-Kai Cheng, Daniel Raftery, Jiyang Dong*. NMF-based approach for missing values imputation of mass spectrometry metabolomics data. Molecules, 2021, 26(19): 5787. (2区)
Chao Zhao, Lei Guo, Jiyang Dong*, Zongwei Cai*. Mass spectrometry imaging-based multi-modal technique: The next-generation of biochemical analysis strategy. The Innovation, 2021, 2(4): 100151(1区top)
Yuhan Hu, Xinlin Zhang, Dicheng Chen, Zhiping Yan, Xiaoyong Shen, Gen Yan, Lin Ou-yang, Jianzhong Lin, Jiyang Dong, Xiaobo Qu*. Spatiotemporal Flexible Sparse Reconstruction for Rapid Dynamic Contrast-enhanced MRI. IEEE Transactions on Biomedical Engineering, 2021. doi:10.1109/TBME.2021.3091881 (2区)
Lingli Deng, Lei Ma, Kian-Kai Cheng, Xiangnan Xu, Daniel Raftery, Jiyang Dong*. A Sparse PLS-based Method for Overlapping Metabolite Set Enrichment Analysis. Journal of Proteome Research. 2021, 20(6): 3204–3213 (2区)
Lei Guo#, Zhenxing Hu#, Chao Zhao*, Xiangnan Xu, Shujuan Wang, Jingjing Xu, Jiyang Dong, Zongwei Cai. Data filtering and its prioritization in pipelines for spatial segmentation of mass spectrometry imaging. Analytical Chemistry. 2021, 93(11): 4788–4793 (1区top)
Dongbao Liu, Yonggui Yang, Dicheng Chen, Zi Wang, Di Guo, Lijun Bao, Jiyang Dong, Xiaobo Qu*. Brain metabolic differences between temporal lobe epileptic seizures and organic non-epileptic seizures in postictal phase: A retrospective study with magnetic resonance spectroscopy. Quantitative Imaging in Medicine and Surgery, 2021, 11(8):3781-3791 (2区)
Jian Zuo#, Mengqing Tao#, Xinyue Wu, Tiantian Jiang, Opeyemi Joshua Olatunji, Jiyang Dong, Jun Han*, Cong-Lan Ji*. Securidaca inappendiculata-Derived Xanthones Protected Joints from Degradation in Male Rats with Collagen-Induced Arthritis by Regulating PPAR-γ Signaling. Journal of Inflammation Research, 2021, 14: 395 – 411. (2区)
Lei Guo, Yongpei Wang, Xiangnan Xu, Kian-Kai Cheng, Yichi Long, Jingjing Xu, Sanshu Li, Jiyang Dong*. DeepPSP: A global-local information based deep neural network for prediction of protein phosphorylation site. Journal of Proteome Research. 2021, 20(1): 346–356 (2区)
Guiping Shen*, Zenan Ding, Tao Dai, Jianghua Feng, Jiyang Dong, Feng Xia, Jingjing Xu, Jidan Ye. Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapia (Oreochromis niloticus). Animal. 2021, 15(3):100167. (2区)
Conglan Ji, Sheng Dai, Hong Liu, Jiyang Dong, Chunsheng Liu, Jian Zuo. Polyphenols from Securidaca inappendiculata alleviated acute lung injury in rats by inhibiting oxidative stress sensitive pathways. Chinese Herbal Medicines. 2021, 13 (2):381-388. (4区)
董继扬, 吴昕玥, 邓伶莉. 一种基于代谢物关联网络的受扰动通路分析方法. 发明专利. ZL 2021 1 1301560.7. 2024.06.28 (授权)
许晶晶, 黄自鑫, 郭磊, 董继扬. 用于预测蛋白质翻译后修饰位点的深度学习方法. 发明专利. ZL 2022 1 0406078.8. 2024.05.31(授权)
董继扬, 郭磊, 胡振兴, 徐向南, 许晶晶. 一种用于质谱成像数据的交互式空间分割方法. 发明专利. ZL 2022 1 0072775.4, 2024.04.06 (授权)
董继扬, 张璇, 邓伶莉, 许晶晶. 一种受扰动代谢通路确定方法及系统. 发明专利. ZL 2020 1 0008409.3, 2023.03.14 (授权)
许晶晶，王远山，董继扬. 一种基于非负矩阵分解的质谱数据缺失值填补方法及系统. 发明专利. ZL 2020 1 0701528.7, 2022.08.12 (授权)
董继扬, 龙怡驰, 邓伶莉. 一种基于圆弧切线模型的核磁共振波谱基线校正方法. 发明专利. ZL 2020 1 1594412.4, 2021.10.29. (授权)
吴彩胜, 袁彩霞, 董继扬, 蒋福全, 林田. 基于三维组合衍生化的质谱数据处理软件(简称：MS-TDF). 计算机软件著作登记证书. 2023SR1410351, 2023.11.09
黄自鑫，许晶晶，董继扬. 扰动代谢子网分析与可视化软件. 计算机软件著作登记证书. 2022SR1397000, 2022.11.10.
